A novel lncrna, luadt1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27

HIGHLIGHTS

  • who: M Qiu from the DepartmentMedical University of Jiangsu Province, Nanjing, China have published the Article: A novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27, in the Journal: (JOURNAL)
  • what: The authors demonstrated that LUADT1 binds to SUZ12 and epigenetically suppresses p27 expression. p27 is a tumor suppressor that regulates cell cycle proliferation and is often downregulated in cancers.
  • how: In the expression cohort of 20 LUAD patients qRT-PCR results showed that the p27 mRNA level negatively correlated with the expression of LUADT1 . This result is consistent . . .

     

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