Induction of apoptosis, g0/g1 phase arrest and microtubule disassembly in k562 leukemia cells by mere15, a novel polypeptide from meretrix meretrix linnaeus

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  • who: Ming Liu from the Institute of Oceanology, Chinese Academy of Science, Nanhai Rd, Qingdao, China have published the article: Induction of Apoptosis, G0/G1 Phase Arrest and Microtubule Disassembly in K562 Leukemia Cells by Mere15, a Novel Polypeptide from Meretrix meretrix Linnaeus, in the Journal: (JOURNAL)
  • what: The authors investigated its activity on human K562 chronic myelogenous leukemia cells. inhibited the growth of K562 cells with IC50 values of 38.2 μg/mL. also caused concentration dependent induction of apoptosis with overproduction of reactive oxygen species and loss of mitochondrial membrane potential. This study . . .

     

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