Ccnd1 mutations increase protein stability and promote

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  • who: Top from the Division of Hematopoietic Stem Cell and Leukemia Research, Gehr Leukemia Center, Beckman Research Institute of City of Hope, Duarte, CA, USA Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA have published the research: CCND1 mutations increase protein stability and promote, in the Journal: (JOURNAL)
  • how: To examine whether increased CCND1 protein levels in these mutant cases was due to the presence of more stable 3′ UTR-truncated transcripts the authors used a previously-described RT-PCR assay to compare full-length and 3′ UTR-truncated . . .

     

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