Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophages

HIGHLIGHTS

  • who: Akari Ishisaka and colleagues from the Faculty of Food Culture, Department of Nutrition, Kurashiki Sakuyo University, Kurashiki, Japan, Department of Bioscience, Faculty of Biotechnology, Fukui have published the article: Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages, in the Journal: PLOS ONE | www.plosone.org of November/19,/2013
  • what: The authors provided a novel pathway for the selective biological activity of quercetin metabolites in macrophages within the inflamed sites and tissues.
  • how: These results showed that mitochondrial dysfunction plays a crucial role in the deconjugation of quercetin glucuronides . . .

     

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