Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

HIGHLIGHTS

  • who: David Brenière-Letuffe from the (UNIVERSITY) have published the paper: Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks, in the Journal: (JOURNAL)
  • what: The authors aimed at visualising the dynamics of this otherwise unnoticed phenomenon of clone number reduction and clonal overgrowth in hiPSC culture using this simple yet effective tool. During the experiment, the splitting ratio of the C25-young cell line had to be lowered for technical reasons to keep all cell lines synchronously at the same passage number. The experiments showed . . .

     

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