HIGHLIGHTS
- who: Olivier Dormond from the (UNIVERSITY) have published the research: The Effects of mTOR-Akt Interactions on Anti-apoptotic Signaling in Vascular Endothelial Cells*, in the Journal: (JOURNAL) of August/10,/2007
SUMMARY
Intracellular signals leading to Akt activation are conserved across species. Upon activation Akt mediates pro-survival and anti-apoptosis in part via the phosphorylation and inhibition of the Bcl-2 homolog BAD, the phosphorylation and inactivation of the FoxO subfamily of forkhead transcription factors, and the transcriptional co-activator Yes-associated protein. Antibodies used for Western blot were anti-phospho . . .
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