Toxoplasma gondii rop18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell p2x1

HIGHLIGHTS

  • who: Li-Juan Zhou from the Department of Pathogen Biology, Guangdong Provincial Key Laboratory University, Guangzhou, Guangdong, People’s Republic of China have published the research work: Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1, in the Journal: (JOURNAL)
  • what: The analysis demonstrated that the Bcl2/Bax ratio at the protein level was significantly elevated by TgROP18 in the mitochondrial fraction (Fig 9), indicating that the release of Cyt C from mitochondria to the cytosol is inhibited by TgROP18.
  • how: The data were analyzed . . .

     

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