HIGHLIGHTS
- who: Mohammadhossein Khorraminejad-Shirazi from the Department of Cardiovascular Medicine, Shiraz University of Medical Sciences, Shiraz, Iran have published the research work: AICAR and nicotinamide treatment synergistically augment the proliferation and attenuate senescence-associated changes in mesenchymal stromal cells, in the Journal: (JOURNAL)
- what: To delay the senescence, increasing autophagy by selective inhibition of mTORC1 seems to be an efficient approach to employ.
- how: In this study to attenuate the aging of the MSCs 5aminoimidazole-4-carboxamide ribonucleotide (AICAR) an AMPK activator and NAM were employed. The authors evaluated the effects of AICAR . . .
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