Tracking a refined eif4e-binding motif reveals angel1 as a new partner of eif4e

HIGHLIGHTS

  • who: Pauline Gosselin et al. from the CNRS, FR2424, ABiMS, France have published the paper: Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E, in the Journal: (JOURNAL)
  • how: To screen for new 4E-IPs the authors developed a novel approach based on structural in silico and biochemical analyses. The eIF4E-binding assay and immunoblot analysis are described in Supplementary
  • future: Taken together the results illustrate that the authors developed a powerful method for identifying new eIF4E partners and open new perspectives for understanding eIF4E-specific regulation.
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