Oxidative deamination of serum albumins by (-)-epigallocatechin-3-o-gallate: a potential mechanism for the formation of innate antigens by antioxidants

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  • who: Yukinori Hatasa et al. from the Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan, PRESTO, Japan have published the Article: Oxidative Deamination of Serum Albumins by (-)-Epigallocatechin-3-O-Gallate: A Potential Mechanism for the Formation of Innate Antigens by Antioxidants, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0153002]. April 5, 2016 of /1371/
  • what: The authors show that oxidative modification of proteins, including oxidative deamination of lysine residues in proteins, could lead to the formation of innate epitopes. The authors analyzed the EGCG-derived intermediates and oxidized amino_acids generated . . .

     

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