Tumor acidity: from hallmark of cancer to target of treatment

HIGHLIGHTS

  • who: Alexey Bogdanov from the Boston College, United States have published the article: Tumor acidity: From hallmark of cancer to target of treatment, in the Journal: (JOURNAL)
  • what: This approach provides the simultaneous restriction of lactate synthesis from both glycolysis and glutaminolysis.
  • future: More research is needed on the mechanisms of the effectiveness of sodium bicarbonate and other buffer solutions in cancer patients.

SUMMARY

    For instance, a decrease in the pHe leads to a decrease in the activity and proliferation of T_cells. In an acidic environment, effector T_cells require . . .

     

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