Shmt2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

HIGHLIGHTS

  • who: Weiyu Kong from the Center for Biotechnology Information to validate theHoĢ‚pital Foch, France Virginia Commonwealth University have published the article: SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma, in the Journal: (JOURNAL)
  • what: This study demonstrated that SHMT2 could promote the infiltration of Treg cells and mediate immune escape.
  • how: Response prediction of anti-tumour drugs To evaluate SHMT2 for pRCC treatment the IC50 of commonly administered anti-tumour drugs in the TCGA project of the pRCC dataset was calculated using the algorithm developed . . .

     

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