Inhibition of bruton s tyrosine kinase alleviates monocrotaline- induced pulmonary arterial hypertension by modulating macrophage polarization

HIGHLIGHTS

  • who: Macrophage Polarization and collaborators from the Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China have published the paper: Inhibition of Bruton s Tyrosine Kinase Alleviates Monocrotaline- Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization, in the Journal: Oxidative Medicine and Cellular Longevity 20000 of 29/08/2022
  • what: This study demonstrated that BGB-3111, a selective BTK inhibitor, can ameliorate MCT-induced PAH and pulmonary vascular remodeling.
  • how: In this study a selective BTK inhibitor (BTKi) BGB-3111 was applied to investigate . . .

     

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