Genetic variants of abc and slc transporter genes and chronic myeloid leukaemia: impact on susceptibility and prognosis

HIGHLIGHTS

• who: Raquel Alves and colleagues from the of Oncobiology and Hematology (LOH), University Clinic of Hematology have published the research work: Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis, in the Journal: (JOURNAL) of 20/09/2014
• what: In the study , these were the two variants with the lowest MAF, but even so, rs2231142 was shown to be positively correlated with CML susceptibility.
• how: All the genetic variants the authors studied have been onserved to induce lower gene_expression or reduced protein activity . The results . . .
  

   

  

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