Promoting remyelination in multiple sclerosis

HIGHLIGHTS

• who: Nick Cunniffe from the Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK have published the article: Promoting remyelination in multiple sclerosis, in the Journal: (JOURNAL)
• what: Reactive astrocytes found at the site of demyelination, for example, secrete inhibitors of remyelination such as Endothelin-1 and the recent description of A1 reactive astrocytes, which contribute to the death of oligodendrocytes , needs to be incorporated into the current model of remyelination and potential therapeutic targets explored. Cell‑based therapies Enhancing the activity of endogenous oligodendrocyte progenitors has proved the most accessible strategy to promote remyelination . . .
  

   

  

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