Il-10-dependent and -independent mechanisms are involved in the cardiac pathology modulation mediated by fenofibrate in an experimental model of chagas heart disease

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  • who: Gerardo A. Mirkin and Nora B. Goren from the Konkuk University, South Korea Nagasaki University, Japan have published the Article: IL-10-Dependent and -Independent Mechanisms Are Involved in the Cardiac Pathology Modulation Mediated by Fenofibrate in an Experimental Model of Chagas Heart Disease, in the Journal: (JOURNAL)
  • what: At weeks 5 and 9 post-infection (pi), echocardiographic studies were carried out to evaluate cardiac dysfunction. Fenofibrate would act in two arenas to preclude its pathological consequences, simultaneously reducing TGF-β and TNF-α and, as the authors show in this manuscript, these effects are independent . . .

     

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