Sialoglycan-binding patterns of bacterial ab5 toxin b subunits correlate with host range and toxicity, indicating evolution independent of a subunits

HIGHLIGHTS

• who: Naazneen Khan et al. from the Powered by the California Digital Library University of California have published the research: Sialoglycan-binding patterns of bacterial AB5 toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits, in the Journal: (JOURNAL) of March/22,/2022
• what: The authors report that A subunit phylogeny evolved independently of B subunits and suggest a future B subunit nomenclature based on bacterial species names. Consistent with much broader host range of Y. pestis, the authors show that YpeB recognizes all mammalian Sia types, except for . . .
  

   

  

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