HIGHLIGHTS
- who: Michael Hamm from the Université UMR3347, Inserm, Signalisation radiobiologie et cancer, Orsay, France, Equipes Labellisées Ligue Contre le Cancer, Paris, France. University of have published the research work: BRN2 is a non-canonical melanoma tumor-suppressor, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors show that BRN2 acts as a tumor suppressor during melanoma initiation and progression in a BRAF-PTEN context since BRN2 and MITF regulate positively and negatively the transcription of PTEN, respectively. The authors report that, consistent with BRN2 playing a key role as a tumor suppressor in . . .
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