Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin a-sarcin in nude mice bearing human colorectal cancer xenografts

HIGHLIGHTS

• who: Jaime TomŁ-Amat from the Human colon carcinoma , and , cells were provided by DrCarl Batt under the partnership Cornell University-Ludwig Institute of Cancer Research. , cells were used as GPA33-positive cells for xenografts induction. Both cell lines were authenticated in , by short tandem repeat (STR) analysis. Cells were also tested by flow cytometry, using a double labelling of , and CD44, characteristic of this cell line, immediately before any in vitro or in vivo assays. Double checking of , expression was also made by western blot using cellular extracts. Human colon adenocarcinoma , (ATCC:HTB-38) and epidermoid . . .
  

   

  

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