Amyloid peptide induced neuroinflammation increases the p2x7 receptor expression in microglial cells, impacting on its functionality

HIGHLIGHTS

  • who: Miguel Díaz-Hernández from the Université Bordeaux, France University of Ferrara, Italy have published the research: Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality, in the Journal: (JOURNAL)
  • what: The authors have evaluated the impact of microglial cells expressing P2X7R on FAD progression analyzing the new transgenic mouse model P2X7R EGFP/J20 mice.
  • how: Showed that EGFP positive cells were mainly found on the GLDG on both genotypes and at all ages tested. The authors found once more in young and adult . . .

     

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