HIGHLIGHTS
- who: Francesca Biagioni and colleagues from the Department of Experimental Oncology, European Institute of Oncology (IEO)-IRCCS, Milan, Italy have published the research: Decoding YAP dependent transcription in the liver, in the Journal: (JOURNAL) of January/05,/2022
- what: The authors report the effort to describe, at the genome-wide level, how YAP reshapes the transcriptional and epigenetic landscape in hepatocytes, thus controlling their proliferation and differentiation. The authors propose that this feed-forward regulation may represent an inherent requirement for the tonic activation of YAP, which is needed to support undifferentiated progenitors during embryonic . . .
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