Mutations associated to antibiotic-resistant helicobacter pylori: it is time to validate sequencing observations

HIGHLIGHTS

  • who: Maxime Pichon and collaborators from the Department University of , Poitiers, France have published the research work: Mutations Associated to Antibiotic-Resistant Helicobacter pylori: It Is Time to Validate Sequencing Observations, in the Journal: (JOURNAL) of 19/07/2022
  • what: As the main genetic supports of antibiotic resistance have been "clearly" identified (plp1 for amoxicillin; 16S rDNA for cyclins, 23S rDNA for clarithromycin, frxA/rdxA for metronidazole, gyrA/B for quinolon, rpoB for rifamycins), the democratization of nucleotide sequencing techniques (Ultra-deep Sequencing) coupled with the development of bioinformatics have recently favored investigations aimed at . . .

     

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