Statistical power considerations in genotype-based recall randomized controlled trials

HIGHLIGHTS

  • who: Naeimeh Atabaki-Pasdar from the DepartmentLund University have published the paper: Statistical power considerations in genotype-based recall randomized controlled trials, in the Journal: Nutrition,
  • what: The authors provide an online power calculator (https://gbr-power.crc.med.lu.se), through which power or sample size can be calculated for other scenarios (more/less SNPs, lower MAFs, and different outcomes). Using the population parameters and effect estimates from the DPP for time-to-event9 and quantitative10 outcome variables, the authors demonstrate through simulations that the GBR approach is ubiquitously more powerful than the conventional . . .

     

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