Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin*

HIGHLIGHTS

  • who: Outi K. Heikkinen from the (UNIVERSITY) have published the research: Atomic Structures of Two Novel Immunoglobulin-like Domain Pairs in the Actin Cross-linking Protein Filamin*, in the Journal: (JOURNAL) of September/11,/2009
  • how: The SAXS results showed that IgFLNa16 -17 and 18 -19 form tightly interacting domain pairs whereas domains 22-23 do not exhibit such domain packing.

SUMMARY

    Mice with targeted deletion of any of the filamin genes die either during development or soon after birth. The platelet von Willebrand factor receptor, glycoprotein (GP) Ib␣, interacts in . . .

     

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