SUMMARY
Has been estimated at 9.2 per 100,000 adults with a slight predominance in males, making it a common encounter in clinical practice. Likely originating from the lateral epithelium of the tympanic membrane, cholesteatoma forms in the pneumatized aspects of the temporal bone, where it tends to grow into expansive and destructive masses leading to erosion of local bone and soft tissue structures. As a high number of mineralized osteocyte lacunae has been previously reported as a sign of overall low bone remodeling and premature aging of the bone matrix in auditory ossicles, the results suggest . . .
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