Systematic elucidation of the multi-target pharmacological mechanism of terminalia arjuna against congestive cardiac failure via network pharmacology and molecular modelling approaches

SUMMARY

The Indian Medicinal Plants, Phyto-chemistry Additionally, Therapeutics (IMPPAT)(Mohanraj et_al 2018), and KNApSAcK(Nakamura et_al 2013)databases were used to gather data on the active ingredients of T. arjuna. Screening for Potential Target Genes for Terminalia arjuna Active Constituents against CHF Using Swiss Target Prediction (Gfeller et_al 2014) and STITCH databases (Szklarczyk et_al 2016) potential targets for the active compounds of T. arjuna were identified. The online platform of Swiss Target Prediction used the SMILES number of each constituent to obtain targets using the reverse pharmacophore matching method. The network of active components of T. arjuna . . .

 



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