Modeling of shotgun sequencing of dna plasmids using experimental and theoretical approaches

HIGHLIGHTS

  • who: Sergey Shityakov from the Department of, University of Würzburg, Würzburg, Germany have published the research: Modeling of shotgun sequencing of DNA plasmids using experimental and theoretical approaches, in the Journal: (JOURNAL)
  • what: The authors demonstrate the statistical significance of the results .
  • how: The authors implemented the virtual sequencing algorithm based on the Sanger methodology to correctly predict and emphasize the performance of this DNA sequencing technique using the average sequence length for the adjustment of coverage values in experimental settings. The authors applied a novel algorithm to simulate shotgun sequencing . . .

     

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