HIGHLIGHTS
- who: Julia Ponce from the (UNIVERSITY) have published the research: Transmembrane Domain III Plays an Important Role in Ion Binding and Permeation in the Glycine Transporter GLYT2*, in the Journal: (JOURNAL) of December/17,/1999
- what: The authors report in this paper that tyrosine at position 289 of GLYT2a is crucial for ion coupling, glycine affinity and sodium selectivity, stressing the essential role played by this residue of transmembrane domain III in the mechanism of transport. The authors show that Tyr289 replacement either by Phe or Ser has a dramatic effect in glycine binding and . . .
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