Mesenchymal stem cell-derived exosomes improve motor function and attenuate neuropathology in a mouse model of machado-joseph disease

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  • who: Hua-Jing You from the Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, No, Zhongshan Road, Guangzhou, Guangdong, China have published the Article: Mesenchymal stem cell-derived exosomes improve motor function and attenuate neuropathology in a mouse model of Machado-Joseph disease, in the Journal: (JOURNAL)
  • what: The authors aim to investigate whether MSC-derived exosomes can slow down the disease progression in a transgenic mouse model of MJD. In the present study, YACMJD84.2 mice developed motor deficits as evidenced by the decline in rotarod performance at the age of 14 . . .

     

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