HIGHLIGHTS
- who: Hannes Maib from the University of Cell and Developmental Biology, Dow Street, Dundee , EH, UK have published the article: A mechanism for exocyst-mediated tethering via Arf6 and PIP5K1C-driven phosphoinositide conversion, in the Journal: (JOURNAL) of July/11,/2022
- what: The authors determine each subcomplex independently binds to phosphatidylinositol 4 5-bisphosphate (PI(4 5)P2) which is minimally sufficient for membrane tethering. The authors show that each subcomplex independently binds to PI(4,5) P2 and that the holocomplex is able to tether two opposing PI(4,5)P2-positive membranes. The . . .
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