HIGHLIGHTS
- who: Chris Arter from the (UNIVERSITY) have published the research work: Structural features of the protein kinase domain and targeted binding by small-molecule inhibitors, in the Journal: (JOURNAL) of November/27,/2021
- how: The authors review the different types of protein kinase inhibitors in the context of the different structural and functional states of protein_kinases and give examples to show how these features can be exploited in the development of kinase inhibitors.
SUMMARY
The catalytic activity of protein_kinases is regulated, and they can be thought of as molecular switches that . . .
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