Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter*

HIGHLIGHTS

  • who: Chung S. Song from the (UNIVERSITY) have published the research: Tissue-specific and Androgen-repressible Regulation of the Rat Dehydroepiandrosterone Sulfotransferase Gene Promoter*, in the Journal: (JOURNAL) of April/13,/1998
  • what: The authors show that the liver-selective activity of this gene is retained even with a much shorter promoter fragment.
  • how: To identify the negative androgen response region (nARR) responsible for the hormonal repression a nested set of 59-deleted Std promoter fragments were tested for activity in HepG2 cells in the presence or absence of DHT. Of this study . . .

     

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