Sip30 is regulated by erk in peripheral nerve injury-induced neuropathic pain*

HIGHLIGHTS

• who: Guangdun Peng from the (UNIVERSITY) have published the research: SIP30 Is Regulated by ERK in Peripheral Nerve Injury-induced Neuropathic Pain*, in the Journal: (JOURNAL) of October/30,/2009
• what: The authors show that SIP30 is regulated by ERK through the recruitment of cyclic AMP-response element-binding protein (CREB) to the promoter of the sip30 gene, providing a novel mechanism by which ERK regulates CCI-induced neuropathic pain. threshold; PWL, paw withdrawal latency; LTP, long term potentiation; DN, dominant negative; CA, constitutively active. The authors show that CCI-induced upregulation of SIP30 correlates . . .
  

   

  

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