Synthesis and biological activity of some new 1,3,4-thiadiazole and 1,2,4-triazole compounds containing a phenylalanine moiety

HIGHLIGHTS

• who: Mihaela Moise from the Department of Organic Chemistry and Biochemistry, Faculty of Chemistry, "AlICuza", , have published the article: Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety, in the Journal: Molecules 2009, 14, 2621-2631 of 11/05/2009
• what: New 1,3,4-thiadiazole (6-7) and 1,2,4-triazole (8-9) compounds having a D,L-phenylalanine moiety were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazide in acid and alkaline medium, respectively.

SUMMARY

 



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