Rassf1c oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a src/rho axis

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  • who: RASSF et al. from the (UNIVERSITY) have published the Article: RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis, in the Journal: (JOURNAL) of 17/09/2021
  • what: The authors show that the novel RASSF1C drives transition and stem cell attributes in breast cancer cells. The authors demonstrate that RASSF1C-induced cells display increased expression of cancer stem-like markers such as CD133 ALDH1 and Nanog and are accompanied by higher invasive potential in vitro and in vivo. The authors propose the use of gene promoter methylation . . .

     

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