HIGHLIGHTS
- who: Hani Oweira et al. from the Department of Surgery, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany have published the research work: Kynurenine Is the Main Metabolite of Tryptophan Degradation by Tryptophan 2,3-Dioxygenase in HepG2 Tumor Cells, in the Journal: (JOURNAL)
- what: The authors investigated Trp degradation to Kyn by IDO and TDO in primary human hepatocytes (PHH) and tumoral HepG2 cells.
- future: The authors believe that high Trp levels in the medium inhibited cell metabolism but further experiments are needed to confirm this. More research is needed to determine . . .
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