Therapy-induced senescent/polyploid cancer cells undergo atypical divisions associated with altered expression of meiosis, spermatogenesis and emt genes

HIGHLIGHTS

  • who: Joanna Czarnecka-Herok and collaborators from the Laboratory of Molecular Bases of Ageing, Nencki Institute of Experimental Biology, Polish Academy of have published the research: Therapy-Induced Senescent/Polyploid Cancer Cells Undergo Atypical Divisions Associated with Altered Expression of Meiosis, Spermatogenesis and EMT Genes, in the Journal: (JOURNAL) of 25/05/2022
  • what: The authors sought to further characterize the cells undergoing senescence/polyploidization and their propensity for atypical divisions. Now, the authors show that the IRI-treated MCF-7 cell population underwent temporal inhibition of proliferation . With the use of SBEM combined with . . .

     

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