Loss of foxa2 induces er stress and hepatic steatosis and alters developmental gene expression in human ipsc-derived hepatocytes

HIGHLIGHTS

• who: Maryam Aghadi from the (UNIVERSITY) have published the research work: Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes, in the Journal: (JOURNAL) of 28/Dec/2021
• what: The analysis showed a significant decrease in glucose uptake in FOXA2-/-MH, suggesting that FOXA2 plays an Cell Death and Disease 13:713 7 important role in glucose metabolism in human hepatocytes (Fig 4E).
• how: Interestingly the immunostaining results showed that the majority of the Ki67+ cells were co-localized with the hepatic marker . . .
  

   

  

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