Dna methylation profiles of gad1 in human cerebral organoids of autism indicate disrupted epigenetic regulation during early development

HIGHLIGHTS

  • who: Georgina Pearson and collaborators from the Laboratory for Neuronal Circuit Dynamics, Imperial College London, London , NN, UK Department of Psychiatry, Department of Clinical Research, University of Southern Denmark have published the research work: DNA Methylation Profiles of GAD1 in Human Cerebral Organoids of Autism Indicate Disrupted Epigenetic Regulation during Early Development, in the Journal: (JOURNAL) of 30/04/2022
  • what: To address this, here the authors focused specifically on a functionally relevant regulatory region of GAD1 and observed distinct differences in the DNA methylation profiles of cerebral organoids derived from ASD and control subjects . . .

     

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