Structural basis for non-canonical integrin engagement by bordetella adenylate cyclase toxin

HIGHLIGHTS

  • who: Jory A. Goldsmith from the The University of Texas at Austin, Austin, TX, USA have published the Article: Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin, in the Journal: (JOURNAL) of August/16,/2022
  • what: The authors determine a 2.7 Å resolution cryoelectron microscopy (cryo-EM) structure of the ACT receptor-binding domain in complex with the aMb2 ectodomain.
  • how: The complex was then plunge-frozen on 1.2/1.3 UltrAuFoil grids and a dataset was collected on a Titan Krios using a K3 detector and . . .

     

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