HIGHLIGHTS
- who: Nathan P. Wiederhold from the Fungus Testing Laboratory, Department of Pathology and Laboratory Medicine, University of Texas Health have published the paper: Pharmacodynamics, Mechanisms of Action and Resistance, and Spectrum of Activity of New Antifungal Agents, in the Journal: (JOURNAL)
- what: Currently, there are several antifungals in development for the treatment of invasive mycoses, with some in late-stage clinical trials.
- how: This review discusses the pharmacodynamics (i.e. mechanisms of action) mechanisms of resistance spectrum of activity and the pharmacokinetic/pharmacodynamic (PK/PD) parameters of these agents.
SUMMARY
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