Intradermal immunization of sars-cov-2 original strain trimeric spike protein associated to cpg and addas03 adjuvants, but not mpl, provide strong humoral and cellular response in mice

HIGHLIGHTS

  • who: Luan Firmino-Cruz and collaborators from the Institute of Biophysics Chagas Filho, Federal University of Rio Janeiro (UFRJ), Rio Janeiro, RJ, Brazil have published the research: Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice, in the Journal: Vaccines 2022, 1305 of /2022/
  • what: All these adjuvants have already been tested by the i.m. route , however the authors aimed to evaluate their efficacy along with the S ptn regarding an i.d. route vaccination . . .

     

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