A convex formulation for joint rna isoform detection and quantification from multiple rna-seq samples

HIGHLIGHTS

  • who: Elsa Bernard from the (UNIVERSITY) have published the article: A convex formulation for joint RNA isoform detection and quantification from multiple RNA-seq samples, in the Journal: (JOURNAL)
  • what: The authors propose a new method for solving the isoform deconvolution problem jointly across several samples. The authors demonstrate the benefits of combining several samples on simulated and real data and show that the approach outperforms pooling strategies and methods based on integer programming. When several samples are available, the authors propose to generalize this approach by using a convex penalty that leads to small . . .

     

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