Hormonal regulation of telomerase activity and htert expression in steroid-regulated tissues and cancer

HIGHLIGHTS

  • who: Mohammad Taheri from the (UNIVERSITY) have published the paper: Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer, in the Journal: (JOURNAL)
  • what: These results suggest that the hTERT gene is not a direct progesterone target, and the main reason for the down-regulation of telomerase activity after progesterone treatment is the cell cycle blockage and cell accumulation in the G0/G1-phase .

SUMMARY

    Is required for their proper function and inhibition of DNA damage responses. Naturally, the telomerase-encoding gene, hTERT, shows a silent . . .

     

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