Targeted long-read bisulfite sequencing identifies differences in the tert promoter methylation profiles between tert wild-type and tert mutant cancer cells

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• who: Seungjae Lee et al. from the Department of Pathology, StJude Children's Research Hospital, Memphis, TN, USA Department of Surgery, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA have published the Article: Targeted Long-Read Bisulfite Sequencing Identifies Differences in the TERT Promoter Methylation Profiles between TERT Wild-Type and TERT Mutant Cancer Cells, in the Journal: (JOURNAL)
• what: Because FFPE samples have lower tumor purity, due to admixture of normal cells, and yield more fragmented DNA than cancer cell lines, the authors focused on cancer cell lines to answer this question. The . . .
  

   

  

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