The bile acid membrane receptor tgr5 in cancer: friend or foe?

HIGHLIGHTS

  • who: Youchao Qi and collaborators from the Department Veterinary Medicine, College and Animal Husbandry, University, Xining, China have published the Article: The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?, in the Journal: Molecules 2022, 27, 5292. of 24/07/2022
  • what: Since its identification in 2002, TGR5 has been found to be ubiquitously expressed in humans and animals, and is known to activate various intracellular signaling pathways upon interaction with bile acids.

SUMMARY

    TGR5 overexpression in the gastric cancer cell line SGC7901 activated by 23(S)-mCDCA greatly . . .

     

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