The histone demethylase inhibitor gsk-j4 is a therapeutic target for the kidney fibrosis of diabetic kidney disease via dkk1 modulation

HIGHLIGHTS

  • who: Peir-Haur Hung et al. from the Department of Internal Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan Department of Applied Life Science and Health, Chia-Nan University of Pharmacy and Science have published the article: The Histone Demethylase Inhibitor GSK-J4 Is a Therapeutic Target for the Kidney Fibrosis of Diabetic Kidney Disease via DKK1 Modulation, in the Journal: (JOURNAL) of 20/08/2022
  • what: In this study mechanism of KDM6A was evaluated in streptozotocin-induced diabetic mice. The study provides novel strategy to eliminate fibrosis in kidneys of DKD mice . . .

     

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