Anti-tumor effects of dual pi3k-hdac inhibitor cudc-907 on activation of ros-ire1α-jnk-mediated cytotoxic autophagy in esophageal cancer

HIGHLIGHTS

• who: Zheng Jian from the Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China have published the Article: Anti-tumor effects of dual PI3K-HDAC inhibitor CUDC-907 on activation of ROS-IRE1α-JNK-mediated cytotoxic autophagy in esophageal cancer, in the Journal: (JOURNAL)
• what: The authors aimed to evaluate the anti-tumor effect of CUDC-907 a dual inhibitor in squamous cell carcinoma (ESCC). A working model of the study has been summarized (Fig 7). The results of this study showed that CUDC907 could promote the anti-tumor . . .
  

   

  

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