Increased insulin sensitivity and diminished pancreatic beta-cell function in dna repair deficient ercc1d/  mice

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  • who: Ana P. Huerta Guevara from the Sectionof Molecular and Nutrition, Department of Pediatrics, University of Groningen, University Medical Center Groningen, Hanzeplein, RB Groningen, the Nethelands MN, USA have published the Article: Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1d/  mice, in the Journal: (JOURNAL)
  • what: In this study beta-cell function and insulin sensitivity were studied in Ercc1d/- mice which model a human progeroid syndrome. The authors investigated the effects of DNA damage accumulation on glucose metabolism in this model system. The study provides evidence that endogenous genotoxic . . .

     

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