Carbon nanoparticles adversely affect cftr expression and toxicologically relevant pathways

HIGHLIGHTS

  • who: Torben Stermann from the Institut Heine University have published the Article: Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways, in the Journal: Scientific Reports Scientific Reports
  • what: While performing RNA-Seq data_analysis, the authors focused on differentially expressed genes belonging to apoptosis, DNA damage, cell stress and inflammatory pathways.
  • how: All together these data indicated that the 16HBE14o- cells under ALI condition are able to form an appropriate morphological and functional barrier to model airways in physiological conditions and in response to insults such as toxicants and pathogens.
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